Researchers from China and Scotland have recently published a groundbreaking study that suggests a healthy lifestyle can offset the effects of genetic predisposition to a shorter lifespan by more than 60%. The study, involving over 350,000 adults, highlights the importance of daily choices in maintaining good health and potentially gaining extra years of life.
The study, published in the journal BMJ Evidence-Based Medicine, utilized data from participants recruited via the UK Biobank between 2006 and 2010. Polygenic risk scores were calculated to determine genetic predisposition to living longer or not, while a score associated with a healthy lifestyle was based on factors such as not smoking, moderate alcohol consumption, balanced diet, regular physical activity, and quality sleep.
Participants genetically predisposed to a shorter life were found to be 21% more likely to die prematurely than those predisposed to a longer life expectancy, regardless of their lifestyle choices. However, the study revealed that a healthy lifestyle could counterbalance this genetic risk by more than 60%, potentially extending lifespan by around 5.5 years at the age of 40.
The researchers emphasized the importance of adopting healthy habits early in life to see significant increases in life expectancy. Not smoking, exercising regularly, getting enough sleep, and eating a healthy diet were identified as crucial lifestyle factors in mitigating genetic influences on lifespan.
The study authors stated in a news release, “This study elucidates the pivotal role of a healthy lifestyle in mitigating the impact of genetic factors on lifespan reduction. Public health policies for improving healthy lifestyles would serve as potent complements to conventional healthcare and mitigate the influence of genetic factors on human lifespan.”
Additionally, the study found that participants with unhealthy lifestyles were 78% more likely to die prematurely than those with healthy habits, regardless of genetic predisposition. This underscores the importance of making positive lifestyle choices to improve overall health and longevity.
A similar study conducted last year on over 700,000 individuals aged 40 to 99 suggested that adopting eight healthy habits by the age of 40 could significantly increase lifespan. These habits included being physically active, not smoking, managing stress, eating well, sleeping well, avoiding excessive alcohol consumption, not relying on opioids, and maintaining positive social relationships.
Overall, the research highlights the significant impact of lifestyle choices on longevity and emphasizes the importance of prioritizing health and wellness from an early age. By making conscious decisions to lead a healthy lifestyle, individuals may be able to counteract genetic predispositions to shorter lifespans and potentially gain valuable years of life.